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Why or why not? Are there some cases where is it alright?

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Yeah, in the world of cosmetics... I don't understand what a "mandatory test" is. If it's a product intended for use on the skin, test a small amount on a volunteer's skin. See if it forms a rash. ??? If it's testing for the potential lethality of a product, then they probably shouldn't be using the toxic chemicals in their formula.
If other companies can manage to make cosmetic products without the use of animals, there is no reason that large companies like Proctor & Gamble can't do the same.

And it's funny that you linked to PETA for a list of products not tested by animals. While some of their purposes are actually "ethical" many of them are extremist and some of their actions are considered terrorist attacks. Apparently their ethical treatment of animals excludes the ethical treatment of humans. Just because someone does something that you don't like doesn't mean that you can go firebomb their house and car...
I think that if ethical guidelines are followed it is alright for medications that are necessary to be tested on animals. And when I say necessary I mean heart/kidney/cancer/etc meds. Penis enlargers and diet pills are NOT on this list. With that being said, I don't really understand why we should need to test on animals at all. There are plenty of inmates on death row who have a buttload of time on their hands and nothing to do....
NO. Period.
The other thing to consider is: animal testing is not always even a good indicator of how a product will affect a human. Some things that are toxic to humans, will not bother a guinea pig, some things that bother a mouse, will not affect a human. Different substances are metabolised differently, by different species, so all the animal testing in the world doesn't always make a pharmaceutical (or cosmetic) product safe for human use (The drug Vioxx springs to mind).

With regards to cosmetic animal testing, if they used safe, natural ingredients, there would be no need for such testing. Oh, wait...that costs too much money. Instead they use cheap, chemical fillers, so some form of testing is necessary to make sure it doesn't kill anyone straightaway. (But if the customer dies from cancer in another 10 years time, it wont matter, because it will be impossible to trace the cause, by then...).

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